{"id":1049,"date":"2024-02-25T14:53:33","date_gmt":"2024-02-25T13:53:33","guid":{"rendered":"https:\/\/www.utopiasis.it\/?page_id=1049"},"modified":"2024-03-08T08:17:13","modified_gmt":"2024-03-08T07:17:13","slug":"casrevolution-srl","status":"publish","type":"page","link":"https:\/\/www.utopiasis.it\/en\/casrevolution-srl\/","title":{"rendered":"\u00a0CaSRevolution Srl"},"content":{"rendered":"<p>[et_pb_section fb_built=&#8221;1&#8243; admin_label=&#8221;sezione blocco 1&#8243; _builder_version=&#8221;4.24.2&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;gcid-ac150a38-2027-4fd4-8963-25e8b6f6f839&#8243; custom_margin=&#8221;85px||||false|false&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{%22gcid-ac150a38-2027-4fd4-8963-25e8b6f6f839%22:%91%22background_color%22%93}&#8221;][et_pb_row column_structure=&#8221;1_2,1_2&#8243; use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;1&#8243; make_equal=&#8221;on&#8221; _builder_version=&#8221;4.24.2&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; max_width=&#8221;100%&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.24.2&#8243; _module_preset=&#8221;default&#8221; background_image=&#8221;https:\/\/www.utopiasis.it\/wp-content\/uploads\/2024\/03\/CAS-DT.jpg&#8221; background_enable_video_mp4=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_image src=&#8221;https:\/\/www.utopiasis.it\/wp-content\/uploads\/2024\/03\/CasRevolution.png&#8221; title_text=&#8221;CasRevolution&#8221; _builder_version=&#8221;4.24.2&#8243; _module_preset=&#8221;default&#8221; background_color=&#8221;#FFFFFF&#8221; positioning=&#8221;absolute&#8221; position_origin_a=&#8221;bottom_left&#8221; width=&#8221;35%&#8221; custom_margin=&#8221;||||false|false&#8221; custom_padding=&#8221;20px|20px|20px|20px|false|false&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{}&#8221;][\/et_pb_image][\/et_pb_column][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.24.2&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;100px|60px|100px|60px|true|true&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.24.2&#8243; _module_preset=&#8221;default&#8221; header_2_text_color=&#8221;gcid-e5dce679-c214-4f4d-9539-b4f3d3cd1a14&#8243; header_2_font_size=&#8221;30px&#8221; custom_margin=&#8221;||0px||false|false&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{%22gcid-e5dce679-c214-4f4d-9539-b4f3d3cd1a14%22:%91%22header_2_text_color%22%93}&#8221;]<\/p>\n<h2>CASREVOLUTION s.r.l.<\/h2>\n<p>[\/et_pb_text][et_pb_divider color=&#8221;gcid-e5dce679-c214-4f4d-9539-b4f3d3cd1a14&#8243; _builder_version=&#8221;4.24.2&#8243; _module_preset=&#8221;default&#8221; custom_margin=&#8221;||0px||false|false&#8221; custom_padding=&#8221;||||false|false&#8221; locked=&#8221;off&#8221; global_colors_info=&#8221;{%22gcid-e5dce679-c214-4f4d-9539-b4f3d3cd1a14%22:%91%22color%22%93}&#8221;][\/et_pb_divider][et_pb_text _builder_version=&#8221;4.24.2&#8243; _module_preset=&#8221;default&#8221; header_4_text_color=&#8221;gcid-b7a20a05-ac47-46ee-846a-44540a53bb38&#8243; header_4_line_height=&#8221;1.4em&#8221; global_colors_info=&#8221;{%22gcid-b7a20a05-ac47-46ee-846a-44540a53bb38%22:%91%22header_4_text_color%22%93}&#8221;]<\/p>\n<h4>CASREVOLUTION SRL: THE CASR RECEPTOR FOR ALZHEIMER&#8217;S TREATMENT<\/h4>\n<p>[\/et_pb_text][et_pb_text _builder_version=&#8221;4.24.2&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#000000&#8243; text_font_size=&#8221;17px&#8221; text_line_height=&#8221;1.8em&#8221; text_orientation=&#8221;justified&#8221; global_colors_info=&#8221;{}&#8221;]<\/p>\n<p>The company has identified a development plan through in-depth literature analyses focused on Alzheimer&#8217;s disease, the CaSR transmembrane receptor, and the possible molecules known to modulate the CaSR receptor response.<\/p>\n<p>Through the conducted research, the company believes, with the support of selected research institutes, it can develop new molecules capable of crossing the blood-brain barrier and thus actively acting on the CaSR transmembrane receptor.<\/p>\n<p>This receptor is apparently responsible for the degeneration of astrocytes and neurons, and therefore Alzheimer&#8217;s disease. These new molecules will be developed from known molecules capable of modulating calcium levels in the body.<\/p>\n<p>[\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=&#8221;1_2,1_6,1_6,1_6&#8243; use_custom_gutter=&#8221;on&#8221; gutter_width=&#8221;1&#8243; make_equal=&#8221;on&#8221; _builder_version=&#8221;4.24.2&#8243; _module_preset=&#8221;default&#8221; width=&#8221;100%&#8221; max_width=&#8221;100%&#8221; custom_padding=&#8221;0px||0px||false|false&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_column type=&#8221;1_2&#8243; _builder_version=&#8221;4.24.2&#8243; _module_preset=&#8221;default&#8221; custom_padding=&#8221;100px|60px|100px|60px|true|true&#8221; global_colors_info=&#8221;{}&#8221;][et_pb_text _builder_version=&#8221;4.24.2&#8243; _module_preset=&#8221;default&#8221; text_text_color=&#8221;#000000&#8243; text_font_size=&#8221;17px&#8221; text_line_height=&#8221;1.8em&#8221; text_orientation=&#8221;justified&#8221; global_colors_info=&#8221;{}&#8221;]The scientific team comprises experienced individuals such as Mario Pelegatti (formerly of GSK) and Mario Varasi (formerly of Genetra).<\/p>\n<p>Additionally, the Board of Directors includes Andrea Pellacani, a physician and manager with thirty years of experience in the United States, currently heading the R&#038;D department at Alfasigma SpA.<\/p>\n<p>Utopia, along with industry professionals like Elena Zambon, Chiara Zambon, and Luca Benatti, invested in May 2023.[\/et_pb_text][et_pb_blurb title=&#8221;www.casrevolution.com&#8221; 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Through the conducted research, the company believes, with the support of selected research institutes, it can develop [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_et_pb_use_builder":"on","_et_pb_old_content":"[et_pb_section fb_built=\"1\" admin_label=\"sezione blocco 1\" _builder_version=\"4.24.2\" _module_preset=\"default\" background_color=\"gcid-ac150a38-2027-4fd4-8963-25e8b6f6f839\" custom_margin=\"85px||||false|false\" custom_padding=\"0px||0px||false|false\" global_colors_info=\"{%22gcid-ac150a38-2027-4fd4-8963-25e8b6f6f839%22:%91%22background_color%22%93}\"][et_pb_row column_structure=\"1_2,1_2\" use_custom_gutter=\"on\" gutter_width=\"1\" make_equal=\"on\" _builder_version=\"4.24.2\" _module_preset=\"default\" width=\"100%\" max_width=\"100%\" custom_padding=\"0px||0px||false|false\" global_colors_info=\"{}\"][et_pb_column type=\"1_2\" _builder_version=\"4.24.2\" _module_preset=\"default\" background_image=\"https:\/\/www.utopiasis.it\/wp-content\/uploads\/2024\/03\/CAS-DT.jpg\" background_enable_video_mp4=\"off\" global_colors_info=\"{}\"][et_pb_image src=\"https:\/\/www.utopiasis.it\/wp-content\/uploads\/2024\/03\/CasRevolution.png\" title_text=\"CasRevolution\" _builder_version=\"4.24.2\" _module_preset=\"default\" background_color=\"#FFFFFF\" positioning=\"absolute\" position_origin_a=\"bottom_left\" width=\"35%\" custom_margin=\"||||false|false\" custom_padding=\"20px|20px|20px|20px|false|false\" locked=\"off\" global_colors_info=\"{}\"][\/et_pb_image][\/et_pb_column][et_pb_column type=\"1_2\" _builder_version=\"4.24.2\" _module_preset=\"default\" custom_padding=\"100px|60px|100px|60px|true|true\" global_colors_info=\"{}\"][et_pb_text _builder_version=\"4.24.2\" _module_preset=\"default\" header_2_text_color=\"gcid-e5dce679-c214-4f4d-9539-b4f3d3cd1a14\" header_2_font_size=\"30px\" custom_margin=\"||0px||false|false\" locked=\"off\" global_colors_info=\"{%22gcid-e5dce679-c214-4f4d-9539-b4f3d3cd1a14%22:%91%22header_2_text_color%22%93}\"]\n<h2>CASREVOLUTION s.r.l.<\/h2>\n[\/et_pb_text][et_pb_divider color=\"gcid-e5dce679-c214-4f4d-9539-b4f3d3cd1a14\" _builder_version=\"4.24.2\" _module_preset=\"default\" custom_margin=\"||0px||false|false\" custom_padding=\"||||false|false\" locked=\"off\" global_colors_info=\"{%22gcid-e5dce679-c214-4f4d-9539-b4f3d3cd1a14%22:%91%22color%22%93}\"][\/et_pb_divider][et_pb_text _builder_version=\"4.24.2\" _module_preset=\"default\" header_4_text_color=\"gcid-b7a20a05-ac47-46ee-846a-44540a53bb38\" header_4_line_height=\"1.4em\" global_colors_info=\"{%22gcid-b7a20a05-ac47-46ee-846a-44540a53bb38%22:%91%22header_4_text_color%22%93}\"]\n<h4>CASREVOLUTION SRL: IL RECETTORE CASR PER IL TRATTAMENTO DELL\u2019ALZHEIMER<\/h4>\n[\/et_pb_text][et_pb_text _builder_version=\"4.24.2\" _module_preset=\"default\" text_text_color=\"#000000\" text_font_size=\"17px\" text_line_height=\"1.8em\" text_orientation=\"justified\" global_colors_info=\"{}\"]La societ\u00e0 ha identificato un piano di sviluppo mediante approfondite analisi in letteratura incentrate sulla malattia dell\u2019Alzheimer, sul recettore transmembrana CaSR e sulle possibili molecole ad oggi note che potrebbero modulare la risposta del recettore CaSR. Attraverso le ricerche effettuate la societ\u00e0 ritiene, avvalendosi di istituti di ricerca selezionati, di poter sviluppare, partendo da molecole gi\u00e0 note in grado di modulare i livelli di calcio nell\u2019organismo, nuove molecole capaci di superare la membrana celebrare andando quindi ad agire attivamente sul recettore transmembrana CaSR, apparentemente  responsabile della degenerazione degli astrociti e dei neuroni, e quindi della malattia dell\u2019Alzheimer. [\/et_pb_text][\/et_pb_column][\/et_pb_row][et_pb_row column_structure=\"1_2,1_6,1_6,1_6\" use_custom_gutter=\"on\" gutter_width=\"1\" make_equal=\"on\" _builder_version=\"4.24.2\" _module_preset=\"default\" width=\"100%\" max_width=\"100%\" custom_padding=\"0px||0px||false|false\" global_colors_info=\"{}\"][et_pb_column type=\"1_2\" _builder_version=\"4.24.2\" _module_preset=\"default\" custom_padding=\"100px|60px|100px|60px|true|true\" global_colors_info=\"{}\"][et_pb_text _builder_version=\"4.24.2\" _module_preset=\"default\" text_text_color=\"#000000\" text_font_size=\"17px\" text_line_height=\"1.8em\" text_orientation=\"justified\" global_colors_info=\"{}\"]\n\nIl team scientifico \u00e8 composto da figure con esperienza pluriennale tra cui Mario Pelegatti (ex-GSK) e Mario Varasi (ex-Genetra).\n\nNel Consiglio di amministrazione \u00e8 presente inoltre Andrea Pellacani (medico e manager con esperienza trentennale negli Stati Uniti e ora a capo dell'R&amp;D di Alfasigma SpA).\n\nUtopia ha investito, insieme a professionisti del settore come Elena Zambon, Chiara Zambon e Luca Benatti, nel mese di maggio 2023.\n\n[\/et_pb_text][et_pb_blurb title=\"www.casrevolution.com\" url=\"https:\/\/casrevolution.com\/\" url_new_window=\"on\" use_icon=\"on\" font_icon=\"&#x49;||divi||400\" icon_color=\"gcid-b7a20a05-ac47-46ee-846a-44540a53bb38\" icon_placement=\"left\" _builder_version=\"4.24.2\" _module_preset=\"default\" header_font=\"||||||||\" header_font_size=\"17px\" custom_margin=\"||||false|false\" custom_padding=\"30px||||false|false\" global_colors_info=\"{%22gcid-b7a20a05-ac47-46ee-846a-44540a53bb38%22:%91%22icon_color%22%93}\"][\/et_pb_blurb][\/et_pb_column][et_pb_column type=\"1_6\" _builder_version=\"4.24.2\" _module_preset=\"default\" background_color=\"gcid-e5dce679-c214-4f4d-9539-b4f3d3cd1a14\" custom_padding=\"30px|20px|0px|20px|false|true\" 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